Endoscopic diagnosis and treatment of esophageal leukoplakia: clinical case
https://doi.org/10.31146/2415-7813-endo-66-4-62-65
Abstract
Esophageal leukoplakia is an extremely rare pathological condition of the esophageal mucosa and, at the same time, a lesion that has a high potential for malignization. Currently, there are no generally accepted recommendations for the treatment of patients diagnosed with leukoplakia. However, modern endoscopic techniques allows not only to diagnose this pathology with high accuracy, but also is one of the methods of radical treatment. This clinical observation demonstrates the results of endoscopic diagnosis of esophageal leukoplakia and the option of surgical treatment by argon-plasma coagulation.
About the Authors
R. A. Gagaev
Nizhny Novgorod Regional Clinical Oncological Dispensary
Russian Federation
Russian Federation
S. S. Pirogov
P.A. Herzen Moscow Cancer Research Institute, branch of National Medical Research Radiology Center
Russian Federation
Russian Federation
R. S. Smirnova
Nizhny Novgorod Regional Clinical Oncological Dispensary
Russian Federation
Russian Federation
Yu. A. Evseeva
Nizhny Novgorod Regional Clinical Oncological Dispensary
Russian Federation
Russian Federation
S. V. Gamayunov
Nizhny Novgorod Regional Clinical Oncological Dispensary; A.F. Tsyba MRSC, branch of National Medical Research Radiology Center
Russian Federation
Russian Federation
A. D. Kaprin
P.A. Herzen Moscow Cancer Research Institute, branch of National Medical Research Radiology Center
Russian Federation
Russian Federation
References
1. Singhi A. D., Arnold C. A., Lam-Himlin D. M. et al. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod Pathol. 2017 Nov;30(11):1613-1621. doi: 10.1038/modpathol.2017.73.
2. Kamboj A. K., Gibbens Y. Y., Hagen C. E., Wang K. K., Iyer P. G., Katzka D. A. Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia. Am J Gastroenterol. 2021 Jul 1;116(7):1533-1536. doi: 10.14309/ajg.0000000000001225.
3. Singhi A. D., Arnold C. A., Crowder C. D., Lam-Himlin D. M., Voltaggio L., Montgomery E. A. Esophageal leukoplakia or epidermoid metaplasia: a clinicopathological study of 18 patients. Mod Pathol. 2014 Jan;27(1):38-43. doi: 10.1038/modpathol.2013.100.
4. Ezoe Y., Fujii S., Muto M., Ochiai A., Ohtsu A. Epidermoid metaplasia of the esophagus: endoscopic feature and differential diagnosis. Hepatogastroenterology. 2011 May-Jun;58(107-108):809-13. PMID: 21830395.
5. Dey B., Raphael V., Khonglah Y., Lynrah K. G. Immunohistochemical Analysis of P53 and PRB in Esophageal Squamous Cell Carcinoma. J Clin Diagn Res. 2014 May;8(5): FC01-3. doi: 10.7860/JCDR/2014/7428.4309.
6. Kanagalingam G., Achuo-Egbe Y., Ahmed M. F., Oluaderounmu O., Harley J. A Rare Case of Esophageal Leukoplakia in Achalasia. Cureus. 2022 Apr 1;14(4): e23735. doi: 10.7759/cureus.23735.
7. Meiborg M., Blasberg T., Weber M., Richl J., Freitag D., Wedi E. Endoscopic submucosal dissection for treatment of esophageal leukoplakia reveals hidden histopathology. Endoscopy. 2024 Dec;56(S 01): E278-E279. doi: 10.1055/a-2271-5679.
Review
For citations:
Gagaev R.A., Pirogov S.S., Smirnova R.S., Evseeva Yu.A., Gamayunov S.V., Kaprin A.D. Endoscopic diagnosis and treatment of esophageal leukoplakia: clinical case. Filin’s Clinical endoscopy. 2024;66(4):62-65. (In Russ.) https://doi.org/10.31146/2415-7813-endo-66-4-62-65
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