Clinical observation: papillomatosis and cicatricial stricture of the esophagus
https://doi.org/10.31146/2415-7813-endo-64-3-40-47
Abstract
Purpose To draw the attention of doctors to one of the rare diseases and neoplasms of the esophagus - papillomatosis. Clinical and pathological features of the combination of papillomatosis and cicatricial stricture of the esophagus in one patient as well as treatment options are discussed. Materials, methods and results A 56-year-old patient complained of dysphagia and odynophagia, shortness of breath. In childhood, he came through a tracheostomy and several sessions of bougienage of the esophagus after a chemical burn of the esophagus. Currently, endoscopic examination revealed cicatricial deformity and narrowing of the lumen to 12 mm in the upper third the esophagus, the mucosa is thickened, with papillomatous growths in the form of longitudinal ridges, the structure of the mucosa has a papillary character. Histological examination of the esophageal mucosa shows hyperplasia of the stratified squamous epithelium in the form of multiple polypoid outgrowths with fibrovascular centers, epithelial dysplasia was not detected. The first session of endoscopic bougienage was performed, but thereafter the patient was unable to continue bougienage or any other treatment. Conclusion There are no standard guidelines for the treatment or monitoring of patients with esophageal papillomatosis. Summarizing information from literary sources and our own experience, we consider endoscopic removal of both local single papillomas of the esophagus and widespread papillomatosis.
About the Authors
N. A. Bulganina
Russian Scientific Center of Surgery named after Academician B.V. Petrovsky
Russian Federation
Russian Federation
E. A. Godzello
Russian Scientific Center of Surgery named after Academician B.V. Petrovsky
Russian Federation
Russian Federation
M. V. Khrustaleva
Russian Scientific Center of Surgery named after Academician B.V. Petrovsky
Russian Federation
Russian Federation
References
1. D’Huart M.C., Chevaux J.B., Bressenot A.M. et al. Prevalence of esophageal squamous papilloma (ESP) and associated cancer in northeastern France. Endosc Int Open. 2015, 3:E101-6. doi: 10.1055/s-0034-1390976.
2. Uhlenhopp D.J., Olson K.M., Sunkara T. Squamous cell papilloma of the esophagus: a case series highlighting endoscopic and histologic features. Case Rep Gastrointest Med. 2020, 2020:7645926. doi: 10.1155/2020/7645926.
3. Ekin N., Bestas R., Cetin A. Clinicopathological characteristics of patients with oesophageal squamous papilloma in Turkey and comparison with the literature data: the largest case series ever reported fromTurkey. Int J Clin Pract. 2021;75:e14420. doi: 10.1111/ijcp.14420.
4. Jideh B., Weltman M., Wu Y., Chan C.H. Esophageal squamous papilloma lacks clear clinicopathological associations. World J Clin Cases. 2017;5:134-9. doi: 10.12998/wjcc.v5.i4.134.
5. Ivashkin V.T., Yuschuk N.D., Maev I.V. et al. Clinical Recommendations of the Russian Gastroenterological Association on Diagnosis and Treatment of Infectious Esophagitis. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020; 30(5): 63-83. (in Russ.) doi: 10.22416/1382-4376-2020-30-5-63-83.@@ Ивашкин В.Т., Ющук Н.Д., Маев И.В. и соавт. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению инфекционного эзофагита. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2020;30(5):63-83. doi: 10.22416/1382-4376-2020-30-5-63-83.
6. Ergenç M., Gülşen T., Bahadır F. Esophageal Squamous Cell Papilloma: A Report of Three Cases. Cureus. 2022 May 18; 14(5):e25115. doi: 10.7759/cureus.25115.
7. Lee K.N., Lee O.Y., Lee S.P. Gastrointestinal: Diffuse esophageal papillomatosis involving the entire esophagus. J Gastroenterol Hepatol. 2014 Dec; 29(12): 1951. doi: 10.1111/jgh.12811.
8. Park S.-H., Bang B.-W., Kim H.-G. et al. A Case of Esophageal Squamous Papillomatosis. Korean J Intern Med. 2012 Jun; 27(2): 243. doi: 10.3904/kjim.2012.27.2.243.
9. Bashir A., Suchi M., Martinez A.M. Diffuse Esophageal Papillomatosis. J Pediatr Gastroenterol Nutr. 2022 Dec 1; 75(6): e116. doi: 10.1097/MPG.0000000000003584.
10. Gençdal G., Degirmencioglu S., Akyıldız M. Diffuse Esophageal Squamous Papillomatosis Covering the Entire Esophagus. Clin Gastroenterol Hepatol. 2018 Jun; 16(6): A28. doi: 10.1016/j.cgh.2017.09.020.
11. Batra P.S., Hebert R.L., Haines G.K. et al. Recurrent respiratory papillomatosis with esophageal involvement. Int J Pediatr Otorhinolaryngol. 2001 May 11; 58(3): 233-8. doi: 10.1016/s0165-5876(01)00423-2.
12. Ergenç M., Uprak T.K. Esophagogastroduodenoscopy in patients aged 75 years and older: a single-center study. Cureus. 2022, 14: e21846. doi: 10.7759/cureus.21846.
13. Ottenjann R., Kühner W., Weingart J. Esophageal papilloma - potential precursor of squamous cell carcinoma? [Article in German] Dtsch Med Wochenschr. 1984 Apr 20; 109(16): 613-5. doi: 10.1055/s-2008-1069241.
14. Cohen D.L., Yaakobi R., Shirin H. Squamous papilloma of the proximal oesophagus associated with an inlet patch: a potential aetiological relationship Malays J Pathol 2022; 44(2): 291-294.
15. Mosca S., Manes, G., Monaco R., Bellomo P.F.,Bottino V., Balzano A. Squamous papilloma of the esophagus: long-term follow up. J Gastroenterol Hepatol. 2001; 16(8): 857-61. doi: 10.1046/j.1440-1746.2001.02531.x.
16. Bohn O.L., Saldivar J., Sanchez-Sosa S. Identification of human papillomavirus in esophageal squamous papillomas. World J Gastroenterol. 2008; 14(46):7107. doi: 10.3748/wjg.14.7107.
17. Bucchi D., Stracci F., Buonora N., Masanotti G. Human papillomavirus and gastrointestinal cancer: A review. World J Gastroenterol. 2016; 22(33): 7415-30. doi: 10.3748/wjg.v22.i33.7415.
18. Bakhtiyarov K.R, Shchukina A.S. Human papillum virus - the modern look at the problem. The Journal of scientific articles “Health and Education Millennium”. 2017;19(12):37-42. (in Russ.) doi: 10.26787/nydha-2226-7425-2017-19-12.@@ Бахтияров К.Р., Щукина А.С. Вирус папилломы человека - современный взгляд на проблему. Журнал научных статей «Здоровье и образование в XXI веке». 2017;19(12):37-42. doi: 10.26787/nydha-2226-7425-2017-19-12.
19. Fraga E., Almeida J., Camacho C., Simões J., Bernardes A. A case of esophageal carcinoma due to esophageal squamous papillomatosis. Int J Surg Case Rep. 2020; 71:335-7. 10.1016/j.ijscr.2020.02.057.
20. Ölmez Ş., Aslan M., Güdücüoğlu H., Erten R., Taş A., Sarıtaş B. Esophageal squamous papillomatosis. Wien Klin Wochenschr. 2016;128:447-9. 10.1007/s00508-016-1003-z.
21. Pogorelov N.N., Sokolov V.V., Pirogov S.S., Karpova E.S., Pavlov P.V., Suhin D.G. Papillomatoz pishchevoda: klinicheskoe nablyudenie endoskopicheskoj diagnostiki i lecheniya. Sbornik tezisov k konferencii «Aktual’nye voprosy endoskopii», 2014.@@ Погорелов Н.Н., Соколов В.В., Пирогов С.С., Карпова Е.С., Павлов П.В., Сухин Д.Г. Папилломатоз пищевода: клиническое наблюдение эндоскопической диагностики и лечения. Сборник тезисов к конференции «Актуальные вопросы эндоскопии», 2014.
22. Roden R.B.S., Ling M., Wu T.-C. Vaccination to Prevent and Treat Cervical Cancer. Hum Pathol. 2004 Aug; 35(8): 971-82. doi: 10.1016/j.humpath.2004.04.007.
Review
For citations:
Bulganina N.A., Godzello E.A., Khrustaleva M.V. Clinical observation: papillomatosis and cicatricial stricture of the esophagus. Filin’s Clinical endoscopy. 2023;64(3):40-47. (In Russ.) https://doi.org/10.31146/2415-7813-endo-64-3-40-47
Views:
66
Email this article 