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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая эндоскопия</journal-title><trans-title-group xml:lang="en"><trans-title>Filin’s Clinical endoscopy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2415-7813</issn><publisher><publisher-name>"Global Media technology" Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/2415-7813-endo-64-3-40-47</article-id><article-id custom-type="elpub" pub-id-type="custom">clinendo-105</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Папилломатоз и рубцовая стриктура пищевода. Клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>Clinical observation: papillomatosis and cicatricial stricture of the esophagus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булганина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulganina</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Годжелло</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Godzello</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хрусталева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khrustaleva</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «РНЦХ им. акад. Б.В. Петровского»</institution></aff><aff xml:lang="en"><institution>Russian Scientific Center of Surgery named after Academician B.V. Petrovsky</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2024</year></pub-date><volume>64</volume><issue>3</issue><fpage>40</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Булганина Н.А., Годжелло Э.А., Хрусталева М.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Булганина Н.А., Годжелло Э.А., Хрусталева М.В.</copyright-holder><copyright-holder xml:lang="en">Bulganina N.A., Godzello E.A., Khrustaleva M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://clinendo.elpub.ru/jour/article/view/105">https://clinendo.elpub.ru/jour/article/view/105</self-uri><abstract><p>Цель Привлечь внимание врачей к одной из редких разновидностей заболеваний и новообразований пищевода - папилломатозу. Обсуждаются клинико-патологические особенности сочетания папилломатоза и рубцовой стриктуры пищевода у одного пациента, варианты лечения. Материалы, методы исследования и результаты Пациент 56 лет обратился с жалобами на дисфагию и одинофагию, одышку. В детском возрасте произошел химический ожог пищевода, была выполнена трахеостомия и несколько сеансов бужирования пищевода. В настоящее время при ЭГДС в верхней трети пищевода определяется рубцовая деформация и сужение просвета пищевода до 12 мм, слизистая утолщена, с папилломатозными разрастаниями в виде продольных гребней, структура слизистой имеет сосочковый характер. При гистологическом исследовании в слизистой оболочке пищевода отмечается гиперплазия многослойного плоского эпителия в виде множественных полиповидных выростов с фиброваскулярными центрами, дисплазии эпителия не обнаружено. Был выполнен первый сеанс эндоскопического бужирования, но в дальнейшем пациент не имел возможности продолжить бужирование или какое-либо другое лечение. Заключение Стандартных рекомендаций по лечению или наблюдению за пациентами с папилломатозом пищевода не существует. Резюмируя литературные источники и собственный опыт, мы склоняемся к эндоскопическому удалению как локально-единичных папиллом пищевода, так и распространенного папилломатоза.</p></abstract><trans-abstract xml:lang="en"><p>Purpose To draw the attention of doctors to one of the rare diseases and neoplasms of the esophagus - papillomatosis. Clinical and pathological features of the combination of papillomatosis and cicatricial stricture of the esophagus in one patient as well as treatment options are discussed. Materials, methods and results A 56-year-old patient complained of dysphagia and odynophagia, shortness of breath. In childhood, he came through a tracheostomy and several sessions of bougienage of the esophagus after a chemical burn of the esophagus. Currently, endoscopic examination revealed cicatricial deformity and narrowing of the lumen to 12 mm in the upper third the esophagus, the mucosa is thickened, with papillomatous growths in the form of longitudinal ridges, the structure of the mucosa has a papillary character. Histological examination of the esophageal mucosa shows hyperplasia of the stratified squamous epithelium in the form of multiple polypoid outgrowths with fibrovascular centers, epithelial dysplasia was not detected. The first session of endoscopic bougienage was performed, but thereafter the patient was unable to continue bougienage or any other treatment. Conclusion There are no standard guidelines for the treatment or monitoring of patients with esophageal papillomatosis. Summarizing information from literary sources and our own experience, we consider endoscopic removal of both local single papillomas of the esophagus and widespread papillomatosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эндоскопия</kwd><kwd>папилломатоз пищевода</kwd><kwd>плоскоклеточная папиллома</kwd><kwd>рубцовая стриктура пищевода</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endoscopy</kwd><kwd>esophageal papillomatosis</kwd><kwd>squamous papilloma</kwd><kwd>cicatricial stricture of the esophagus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">D’Huart M.C., Chevaux J.B., Bressenot A.M. et al. Prevalence of esophageal squamous papilloma (ESP) and associated cancer in northeastern France. Endosc Int Open. 2015, 3:E101-6. doi: 10.1055/s-0034-1390976.</mixed-citation><mixed-citation xml:lang="en">D’Huart M.C., Chevaux J.B., Bressenot A.M. et al. 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