clinendoКлиническая эндоскопияFilin’s Clinical endoscopy2415-7813"Global Media technology" Ltd10.31146/2415-7813-endo-67-4-37-43clinendo-661Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL OBSERVATIONSЭозинофильный гастрит у ребенка на фоне редкой генетической патологииEosinophilic gastritis in a child with a rare genetic pathologyКорниенкоЕ. А.KornienkoE. A.elenkornienk@yandex.ruГабрусскаяТ. В.GabrusskayaT. V.noemail@neicon.ruКилинаС. Г.KilinaS. G.noemail@neicon.ruВолковаН. Л.VolkovaN. L.noemail@neicon.ruУлановаН. Б.UlanovaN. B.noemail@neicon.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский Государственный педиатрический медицинский университет» Министерства здравоохранения Российской Федерации“Saint Petersburg state pediatric medical university” of the Ministry of health of the Russian Federation2025240220266743743Copyright © Корниенко Е.А., Габрусская Т.В., Килина С.Г., Волкова Н.Л., Уланова Н.Б., 20262026Корниенко Е.А., Габрусская Т.В., Килина С.Г., Волкова Н.Л., Уланова Н.Б.Kornienko E.A., Gabrusskaya T.V., Kilina S.G., Volkova N.L., Ulanova N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://clinendo.elpub.ru/jour/article/view/661

Эозинофильный гастрит (ЭоГ) - одна из форм эозинофильных гастроинтестинальных заболеваний (ЭГИЗ), рост которых отмечается в последнее десятилетие, в том числе у детей. ЭоГ характеризуется неспецифическими симптомами поражения верхних отделов ЖКТ и эозинофильной инфильтрацией стенки желудка. Поскольку ЭоГ является редким заболеванием, пока не разработаны единые стандарты диагностики, дифференциальной диагностики, лечения и динамического наблюдения за больными. В статье представлены данные о распространенности, патогенезе, основных клинических, эндоскопических и гистологических проявлениях Эо Г. Представлен клинический случай тяжелого ЭоГ у ребенка на фоне редкого генетического заболевания - Нунан-подобного синдрома. Ранее связь эозинофильного поражения ЖКТ, какие-либо аномалии ЖКТ при этом синдроме описаны не были.

Eosinophilic gastritis (EoG) is a form of eosinophilic gastrointestinal diseases (EGID), which has been increasing in the last decade, including in children. EoG is characterized by nonspecific symptoms of upper gastrointestinal tract lesions and eosinophilic infiltration of the gastric wall. Since EoG is a rare disease, uniform standards for diagnosis, differential diagnosis, treatment, and follow-up have not yet been developed. This article presents data on the prevalence, pathogenesis, and main clinical, endoscopic, and histological manifestations of Eo G. A clinical case of severe EoG in a child with a rare genetic disorder, Noonan-like syndrome, is presented. No association between eosinophilic gastrointestinal lesions and any gastrointestinal abnormalities in this syndrome has previously been described.

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The authors declare that there are no conflicts of interest present.