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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая эндоскопия</journal-title><trans-title-group xml:lang="en"><trans-title>Filin’s Clinical endoscopy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2415-7813</issn><publisher><publisher-name>"Global Media technology" Ltd</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">clinendo-378</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Эндоскопическая диагностика болезни Крона тонкой кишки с применением видеокапсульной и баллонной энтероскопии</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>Е. В.</given-names></name></name-alternatives><email xlink:type="simple">katendo@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеев</surname><given-names>М. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернякевич</surname><given-names>П. Л.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кадникова</surname><given-names>У. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цодикова</surname><given-names>О. М.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>Е. Д.</given-names></name></name-alternatives><email xlink:type="simple">efedo@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Российский государственный медицинский университет им. Н И. Пирогова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>09</day><month>12</month><year>2025</year></pub-date><issue>2</issue><fpage>2</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова Е.В., Тимофеев М.Е., Чернякевич П.Л., Кадникова У.А., Цодикова О.М., Федоров Е.Д., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова Е.В., Тимофеев М.Е., Чернякевич П.Л., Кадникова У.А., Цодикова О.М., Федоров Е.Д.</copyright-holder><copyright-holder xml:lang="en">Иванова Е.В., Тимофеев М.Е., Чернякевич П.Л., Кадникова У.А., Цодикова О.М., Федоров Е.Д.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://clinendo.elpub.ru/jour/article/view/378">https://clinendo.elpub.ru/jour/article/view/378</self-uri><abstract><p>В работе представлены данные литературы и первый собственный опыт (п=44) по применению видеокапсульной и баллонно-ассистированной энтероскопии в диагностике болезни Крона тонкой кишки. Рассматриваются эндоскопические диагностические критерии заболевания, позволяющие подтвердить или отвергнуть диагноз болезни Крона, оценить локализацию поражения и его тяжесть. В статье подробно описываются методические аспекты выполнения современных методов энтероскопии, а также результаты их применения в клинической практике. Рассмотрен клинический пример, демонстрирующий осложнение видеокапсульной энтероскопии у пациентки с болезнью Крона, а также возможность его неоперативного разрешения при помощи однобаллонной лапароскопически-ассистированной энтероскопии.</p></abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Белоусова Е.А. Рекомендации по диагностике и лечению болезни Крона //Фарматека. - 2009. - №13. - С.38-44.</mixed-citation><mixed-citation xml:lang="en">Белоусова Е.А. Рекомендации по диагностике и лечению болезни Крона //Фарматека. - 2009. - №13. - С.38-44.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Белоусова Е.А. Язвенный колит и болезнь Крона. Тверь: Триада, 2002. - 128с.</mixed-citation><mixed-citation xml:lang="en">Белоусова Е.А. Язвенный колит и болезнь Крона. Тверь: Триада, 2002. - 128с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Григорьева Г.А., Мешалкина Н.Ю. Болезнь Крона. - М.: Медицина, 2007. - 184с.</mixed-citation><mixed-citation xml:lang="en">Григорьева Г.А., Мешалкина Н.Ю. Болезнь Крона. - М.: Медицина, 2007. - 184с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Дорофеев А.Э. Болезнь Крона: классификация, диагностика и лечение//(астроэнтерология. - 2010. - №313. - С.70-75.</mixed-citation><mixed-citation xml:lang="en">Дорофеев А.Э. Болезнь Крона: классификация, диагностика и лечение//(астроэнтерология. - 2010. - №313. - С.70-75.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Калинина А.В., Хазанова А.И. (астроэнтерология и гепатология: диагностика и лечение. - М.: Миклош, 2009. - 602с.</mixed-citation><mixed-citation xml:lang="en">Калинина А.В., Хазанова А.И. (астроэнтерология и гепатология: диагностика и лечение. - М.: Миклош, 2009. - 602с.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Логинов А.С., Парфенов А.И. Болезни кишечника. - М.: Медицина, 2000. - 630с.</mixed-citation><mixed-citation xml:lang="en">Логинов А.С., Парфенов А.И. Болезни кишечника. - М.: Медицина, 2000. - 630с.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Парфенов А.И. Энтерология. Руководство для врачей. -М.:МИА, 2009. -880с.</mixed-citation><mixed-citation xml:lang="en">Парфенов А.И. Энтерология. Руководство для врачей. -М.:МИА, 2009. -880с.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Притула Н.А. Энтероскопия в диагностике и лечении заболеваний тонкой кишки: Дис.. канд. мед. наук: 14.00.27 /Н.А. Притула; Рос. гос. мед. ун-т. - Москва, 1998. - 187с.</mixed-citation><mixed-citation xml:lang="en">Притула Н.А. Энтероскопия в диагностике и лечении заболеваний тонкой кишки: Дис.. канд. мед. наук: 14.00.27 /Н.А. Притула; Рос. гос. мед. ун-т. - Москва, 1998. - 187с.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Сташук Г.А. Болезнь Крона. Современные методы лучевой диагностики // Материалы образовательного курса для врачей «Воспалительные заболевания кишечника в XXI веке». -М., 2010. - С.45-49.</mixed-citation><mixed-citation xml:lang="en">Сташук Г.А. Болезнь Крона. Современные методы лучевой диагностики // Материалы образовательного курса для врачей «Воспалительные заболевания кишечника в XXI веке». -М., 2010. - С.45-49.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Федоров Е.Д., Иванова Е.В., Тимофеев М.Е., Андреева О.Н. Диагностическая и лечебная эндоскопия тонкой кишки с использованием однобаллонного энтероскопа. Росс, журнал гастроэнт., гепатологии, колопроктологии / Материалы XIV Росс, гастроэнтерологической недели, 2008. - №32. - С. 185.</mixed-citation><mixed-citation xml:lang="en">Федоров Е.Д., Иванова Е.В., Тимофеев М.Е., Андреева О.Н. Диагностическая и лечебная эндоскопия тонкой кишки с использованием однобаллонного энтероскопа. Росс, журнал гастроэнт., гепатологии, колопроктологии / Материалы XIV Росс, гастроэнтерологической недели, 2008. - №32. - С. 185.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Cheifetz A. S. [et al. ] The Risk of Retention of the Capsule Endoscope in Patients with Known or Suspected Crohn's Disease //The American Journal of Gastroenterology. - 2006. - Vol. 101. - P2218-2222.</mixed-citation><mixed-citation xml:lang="en">Cheifetz A. S. [et al. ] The Risk of Retention of the Capsule Endoscope in Patients with Known or Suspected Crohn's Disease //The American Journal of Gastroenterology. - 2006. - Vol. 101. - P2218-2222.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Despotl E.J., Gupta A., Burling D. [et al. ] Effective dilation of small-bowel strictures by double-balloon enteroscopy in patients with symptomatic Crohn's disease (with video) // Gastrointest. Endosc. - 2009. - Vol.70, №5. - P. 1030-6.</mixed-citation><mixed-citation xml:lang="en">Despotl E.J., Gupta A., Burling D. [et al. ] Effective dilation of small-bowel strictures by double-balloon enteroscopy in patients with symptomatic Crohn's disease (with video) // Gastrointest. Endosc. - 2009. - Vol.70, №5. - P. 1030-6.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gert Van Assche, Axel Dignass, Julian PanesThesecond European evidence-based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis Journal of Crohn's and Colitis. - 2010. - Vol.4. - P7-27.</mixed-citation><mixed-citation xml:lang="en">Gert Van Assche, Axel Dignass, Julian PanesThesecond European evidence-based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis Journal of Crohn's and Colitis. - 2010. - Vol.4. - P7-27.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Goldstein J.L., Eisen G.M., Lewis B., Gralnek I., Zlotnick S., Fort J.G. Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo // Clin, Gastroenterol. Hepatol. - 2005. - Vol.3. - P. 13314).</mixed-citation><mixed-citation xml:lang="en">Goldstein J.L., Eisen G.M., Lewis B., Gralnek I., Zlotnick S., Fort J.G. Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo // Clin, Gastroenterol. Hepatol. - 2005. - Vol.3. - P. 13314).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gralnek I. DeFranchis R., Seldman E., Leighton J., Legnani P., Lewis B. Development of a capsule endoscopy scoring index for small intestinal mucosal inflammatory change // Aliment. Pharmacol. Ther. - 2008. - Vol.27. - P.146-154.</mixed-citation><mixed-citation xml:lang="en">Gralnek I. DeFranchis R., Seldman E., Leighton J., Legnani P., Lewis B. Development of a capsule endoscopy scoring index for small intestinal mucosal inflammatory change // Aliment. Pharmacol. Ther. - 2008. - Vol.27. - P.146-154.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hirai F., Beppu Т., Sou S., Seki Т., Yao K., Matsui T. Endoscopic balloon dilatation using double-balloon endoscopy is a useful and safe treatment for small intestinal strictures in Crohn's disease // Dig. Endosc 2010 Vol.22. №3. - P.200-4.</mixed-citation><mixed-citation xml:lang="en">Hirai F., Beppu Т., Sou S., Seki Т., Yao K., Matsui T. Endoscopic balloon dilatation using double-balloon endoscopy is a useful and safe treatment for small intestinal strictures in Crohn's disease // Dig. Endosc 2010 Vol.22. №3. - P.200-4.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kornbluth A. Colombel J.F. Leighton J.A. ICCE consensus for inflammatory bowel disease // Endoscopy. - 2005. - Vol.37. P1051-1054</mixed-citation><mixed-citation xml:lang="en">Kornbluth A. Colombel J.F. Leighton J.A. ICCE consensus for inflammatory bowel disease // Endoscopy. - 2005. - Vol.37. P1051-1054</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Lashner В Clinical features, laboratory findings, and course of Crohn's disease. In: Kirsner JV (ed) Inflammatory bowel disease. 5th ed. Philadelphia: Saunders. - 2000. - P.305-314.</mixed-citation><mixed-citation xml:lang="en">Lashner В Clinical features, laboratory findings, and course of Crohn's disease. In: Kirsner JV (ed) Inflammatory bowel disease. 5th ed. Philadelphia: Saunders. - 2000. - P.305-314.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Lee S.D. The Role of Endoscopy in Inflammatory Bowel Disease //Med. Gen. Med. - 2001. - Vol.3, №4.</mixed-citation><mixed-citation xml:lang="en">Lee S.D. The Role of Endoscopy in Inflammatory Bowel Disease //Med. Gen. Med. - 2001. - Vol.3, №4.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Leighton J.A , Legnani P., Seidman E.G. Role of capsule endoscopy in inflammatory bowel disease: where we are and where we are going // Inflamm. Bowel Dis. - 2007. - Vol. 13, № 3. - P331-7.</mixed-citation><mixed-citation xml:lang="en">Leighton J.A , Legnani P., Seidman E.G. Role of capsule endoscopy in inflammatory bowel disease: where we are and where we are going // Inflamm. Bowel Dis. - 2007. - Vol. 13, № 3. - P331-7.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis B., Eisen G., Friedman S. A pooled analysis to evaluate results of capsule endoscopy trials // Endoscopy. - 2005. -Vol.37. - P.960-965.</mixed-citation><mixed-citation xml:lang="en">Lewis B., Eisen G., Friedman S. A pooled analysis to evaluate results of capsule endoscopy trials // Endoscopy. - 2005. -Vol.37. - P.960-965.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Mergener K., Ponchon Т., Gralnek I. [et al. ] Literature review and recommendations for clinical application of small-bowel capsule endoscopy, based on a panel discussion by international experts: consensus statements for small-bowel capsule endoscopy 2006/2007 // Endoscopy. - 2007. - Vol.39. - P895-909.</mixed-citation><mixed-citation xml:lang="en">Mergener K., Ponchon Т., Gralnek I. [et al. ] Literature review and recommendations for clinical application of small-bowel capsule endoscopy, based on a panel discussion by international experts: consensus statements for small-bowel capsule endoscopy 2006/2007 // Endoscopy. - 2007. - Vol.39. - P895-909.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Pulimood A., Peter S., Rook G., Donoghue H. In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease // Am. J. Clin. Pathol. - 2008. - Vol. 129. -R846-851.</mixed-citation><mixed-citation xml:lang="en">Pulimood A., Peter S., Rook G., Donoghue H. In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease // Am. J. Clin. Pathol. - 2008. - Vol. 129. -R846-851.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ramzan NN. Leighton J.A , Heigh R. I , [etal] Clinical significance of granuloma in Crohn's disease // Inflamm. Bowel Dis. - 2002. -Vol.8 - P. 168-73.</mixed-citation><mixed-citation xml:lang="en">Ramzan NN. Leighton J.A , Heigh R. I , [etal] Clinical significance of granuloma in Crohn's disease // Inflamm. Bowel Dis. - 2002. -Vol.8 - P. 168-73.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Roberto de Franchis, Blair S. Lewis, Daniel S. Mishkin Capsule Endoscopy Simplified - Slack Inc. - 2010. - 160p.</mixed-citation><mixed-citation xml:lang="en">Roberto de Franchis, Blair S. Lewis, Daniel S. Mishkin Capsule Endoscopy Simplified - Slack Inc. - 2010. - 160p.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Semrad C. Role of double balloon enteroscopy in Crohn's disease //Gastrointest. Endosc. - 2007. - Suppl.66. - P.94-95.</mixed-citation><mixed-citation xml:lang="en">Semrad C. Role of double balloon enteroscopy in Crohn's disease //Gastrointest. Endosc. - 2007. - Suppl.66. - P.94-95.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Solem C., Loftus E., Fletcher J. [et al. ] Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial //Gastrointest. Endosc. - 2008 - Vol.68. - R255-266</mixed-citation><mixed-citation xml:lang="en">Solem C., Loftus E., Fletcher J. [et al. ] Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial //Gastrointest. Endosc. - 2008 - Vol.68. - R255-266</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Stange E.F., Travis S., Vermeire S. European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis // Gut 2006 Vol. 55. Suppl.l. P.i 1 -i 15.</mixed-citation><mixed-citation xml:lang="en">Stange E.F., Travis S., Vermeire S. European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis // Gut 2006 Vol. 55. Suppl.l. P.i 1 -i 15.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Triester S.L., Leighton J.A., LeontiadisG.I. [etal] A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn's disease//Am. J, Gastroenterol - 2006. Vol. 101 - P.954-964</mixed-citation><mixed-citation xml:lang="en">Triester S.L., Leighton J.A., LeontiadisG.I. [etal] A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn's disease//Am. J, Gastroenterol - 2006. Vol. 101 - P.954-964</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
