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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая эндоскопия</journal-title><trans-title-group xml:lang="en"><trans-title>Filin’s Clinical endoscopy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2415-7813</issn><publisher><publisher-name>"Global Media technology" Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/2415-7813-endo-67-3-67-73</article-id><article-id custom-type="elpub" pub-id-type="custom">clinendo-252</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Рак желудка у пациентов молодого возраста: клинические и эндоскопические особенности</article-title><trans-title-group xml:lang="en"><trans-title>Gastric cancer in young patients: clinical and endoscopic features</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-2609-3758</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паронян</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Paronyan</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">mparonyan@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8101-2155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пирогов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pirogov</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3174-7695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рябцева</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryabtseva</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-6457-8292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минибаева</surname><given-names>Г. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Minibaeva</surname><given-names>G. F.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7580-5039</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сухин</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhin</surname><given-names>D. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8301-4528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хомяков</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomyakov</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3573-6996</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колобаев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolobaev</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1037-2364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рябов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryabov</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2674-0416</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суркова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Surkova</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8784-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт имени П.А. Герцена - филиал ФГБУ «НМИЦ радиологии» Минздрава России</institution></aff><aff xml:lang="en"><institution>P.A. Hertsen Moscow Oncology Research Institute - branch of the national Medical Research Radiological Center of the Ministry of Health of Russia</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2025</year></pub-date><volume>67</volume><issue>3</issue><fpage>67</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Паронян М.А., Пирогов С.С., Рябцева В.И., Минибаева Г.Ф., Сухин Д.Г., Хомяков В.М., Колобаев И.В., Рябов А.Б., Суркова В.С., Каприн А.Д., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Паронян М.А., Пирогов С.С., Рябцева В.И., Минибаева Г.Ф., Сухин Д.Г., Хомяков В.М., Колобаев И.В., Рябов А.Б., Суркова В.С., Каприн А.Д.</copyright-holder><copyright-holder xml:lang="en">Paronyan M.A., Pirogov S.S., Ryabtseva V.I., Minibaeva G.F., Sukhin D.G., Khomyakov V.M., Kolobaev I.V., Ryabov A.B., Surkova V.S., Kaprin A.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://clinendo.elpub.ru/jour/article/view/252">https://clinendo.elpub.ru/jour/article/view/252</self-uri><abstract><p>Введение: рак желудка у пациентов молодого возраста представляет собой особый интерес ввиду ряда клинических и эндоскопических особенностей. Несмотря на общую тенденцию к снижению заболеваемости раком желудка, в последние годы наблюдается устойчивый рост случаев заболевания среди молодых пациентов, что определяет актуальность изучения особенностей данной патологии. Цель исследования: продемонстрировать результаты анализа данных эндоскопической диагностики случаев рака желудка, обнаруженных у пациентов в возрасте до 30 лет в условиях отделения эндоскопии МНИОИ им. П.А. Герцена. Материалы и методы: проведен ретроспективный анализ 27 случаев рака желудка у пациентов до 30 лет, обследованных в МНИОИ им. П.А. Герцена в период 2012-2024 гг. Использовалось эндоскопическое оборудование экспертного класса с технологией близкофокусной узкоспектральной эндоскопии (NBI Near Focus). Результаты: в 100% случаев наблюдались инфильтративные формы роста (70% - тип III по Borrmann-классификации, 30% - тип IV). Тотальное поражение желудка выявлено в 41% случаев, с распространением на пищевод и/или двенадцатиперстную кишку в 45% из них. 60% случаев диагностированы на IV стадии. Гистологически преобладала низкодифференцированная аденокарцинома с компонентом перстневидных клеток (89%). Выявлен один случай ассоциации опухоли с синдромом Линча. Заключение: рак желудка у молодых пациентов характеризуется агрессивным течением и преобладанием инфильтративных форм, что требует разработки специальных алгоритмов ранней диагностики и повышенной онкологической настороженности.</p></abstract><trans-abstract xml:lang="en"><p>Introduction: Gastric cancer in young patients is of particular interest due to a number of clinical and endoscopic features. Despite of the general downward trend in gastric cancer incidence, in recent years there has been a steady increase in cases among young patients, which determines the relevance of studying the characteristics of this pathology. Objective: Evaluation of the results of endoscopic diagnostics of cases of gastric cancer detected in patients under 30 years of age in the endoscopy department of the P.A. Hertsen Moscow Oncology Research Institute. Materials and methods: A retrospective analysis of 27 cases of gastric cancer in patients under 30 years of age examined at the P.A. Hertsen Moscow Oncology Research Institute in the period 2012-2024 was conducted. Expert-class endoscopic equipment with near-focus endoscopy technology (NBI Near Focus) was used. Results: Infiltrative forms were observed in 100% of cases (70% - type III according to Borrmann classification, 30% - type IV). Total gastric involvement was detected in 41% of cases, with extension to the esophagus and/or duodenum in 45% of them. 60% of cases were diagnosed at stage IV. Histologically - poorly differentiated adenocarcinoma with a signet ring cell component predominated (89%). A case of association with Lynch syndrome was identified. Conclusion: Gastric cancer in young patients is characterized by an aggressive course and a predominance of infiltrative forms, which requires the development of special algorithms for early diagnosis and increased oncological alertness.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>эндоскопия</kwd><kwd>молодой возраст</kwd><kwd>классификация Borrmann</kwd><kwd>инфильтративный рост</kwd><kwd>перстневидноклеточный рак</kwd><kwd>синдром Линча</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric cancer</kwd><kwd>endoscopy</kwd><kwd>young age</kwd><kwd>Borrmann classification</kwd><kwd>infiltrative growth</kwd><kwd>signet ring cell carcinoma</kwd><kwd>Lynch syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">[Malignant neoplasms in Russia in 2023 (incidence and mortality)] / eds by A.D. Kaprin et al. - Moscow: P.A. 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