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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая эндоскопия</journal-title><trans-title-group xml:lang="en"><trans-title>Filin’s Clinical endoscopy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2415-7813</issn><publisher><publisher-name>"Global Media technology" Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/2415-7813-endo-66-4-13-22</article-id><article-id custom-type="elpub" pub-id-type="custom">clinendo-186</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДЕТСКАЯ ЭНДОСКОПИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PEDIATRIC ENDOSCOPY</subject></subj-group></article-categories><title-group><article-title>Профилактика кровотечений из варикозно расширенных вен пищевода</article-title><trans-title-group xml:lang="en"><trans-title>Prevention of bleeding from varicose veins of the esophagus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8305-7592</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лохматов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lokhmatov</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-4451-856X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лузганова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Luzganova</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5730-3684</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">korolevg.a@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4299-3269</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тупыленко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tupylenko</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8805-8164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олдаковский</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Oldakovskiy</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7379-7298</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Будкина</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Budkina</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России; ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России (Сеченовский Университет)</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Children’s Health; First Moscow State Medical University named after I. M. Sechenov, (Sechenov University)</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России (Сеченовский Университет)</institution></aff><aff xml:lang="en"><institution>First Moscow State Medical University named after I. M. Sechenov, (Sechenov University)</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Children’s Health</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>06</day><month>03</month><year>2025</year></pub-date><volume>66</volume><issue>4</issue><fpage>13</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лохматов М.М., Лузганова В.С., Королев Г.А., Тупыленко А.В., Олдаковский В.И., Будкина Т.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Лохматов М.М., Лузганова В.С., Королев Г.А., Тупыленко А.В., Олдаковский В.И., Будкина Т.Н.</copyright-holder><copyright-holder xml:lang="en">Lokhmatov M.M., Luzganova V.S., Korolev G.A., Tupylenko A.V., Oldakovskiy V.I., Budkina T.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://clinendo.elpub.ru/jour/article/view/186">https://clinendo.elpub.ru/jour/article/view/186</self-uri><abstract><p>Актуальность. Кровотечение из варикозно расширенных вен пищевода (ВРВП) и желудка (ВРВЖ) занимает второе место среди причин желудочно-кишечного кровотечения. У пациентов с циррозом печени и портальной гипертензией (ПГ) кровотечение из ВРВП и ВРВЖ в 20% случаев в течение шести недель приводит к смерти. Для избежания кровотечений необходимо проводить первичную и вторичную профилактику. В данном литературном обзоре будут представлены причины ПГ и методы профилактики кровотечений из ВРВП. Цель. Определить мировые тенденции в отношении профилактики кровотечений из ВРВП и ВРВЖ при ПГ. Заключение. В ходе анализа литературы мы пришли к выводу, что преимущество надо отдавать комбинированным методам профилактики. Большинство имеющихся данных посвящено профилактике кровотечений из варикозно расширенных вен пищевода и желудка у взрослых. В настоящее время нет единой выработанной стратегии для профилактики кровотечений из ВРВП и ВРВЖ у детей.</p></abstract><trans-abstract xml:lang="en"><p>Relevance. Bleeding from varicose veins of the esophagus ranks second among the causes of gastrointestinal bleeding. In patients with cirrhosis of the liver and portal hypertension, bleeding from varicose veins of the esophagus and stomach leads to death in 20% of cases within six weeks. Primary and secondary prevention should be carried out to avoid bleeding. This literature review will present the causes of portal hypertension and methods of preventing bleeding from varicose veins of the esophagus. The purpose of this study is to identify global trends in the prevention of bleeding from varicose veins of the esophagus in portal hypertension. Conclusion: During the analysis of the literature, we came to the conclusion that the advantage should be given to combined methods of prevention. Most of the available data is extrapolated from adult studies. Currently, there is no single developed strategy for the prevention of bleeding from varicose veins of the esophagus in children.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>желудочно-кишечные кровотечения</kwd><kwd>портальная гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>esophagogastric variceal bleeding</kwd><kwd>portal hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kamboj A. K., Hoversten P., Leggett C. L. Upper Gastrointestinal Bleeding: Etiologies and Management. Mayo Clin Proc. 2019 Apr;94(4):697-703. doi: 10.1016/j.mayocp.2019.01.022.</mixed-citation><mixed-citation xml:lang="en">Kamboj A. K., Hoversten P., Leggett C. L. Upper Gastrointestinal Bleeding: Etiologies and Management. 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