References

clinendo

Клиническая эндоскопия

Filin’s Clinical endoscopy

2415-7813

"Global Media technology" Ltd

10.31146/2415-7813-endo-66-3-31-38

clinendo-171

Research Article

ГАСТРОЭНТЕРОЛОГИЯ

GASTROENTEROLOGY

Быстрый уреазный тест по правилам и без

Rapid urease test according to the rules and without

https://orcid.org/0000-0003-4629-4836

Назаров

В. Е.

Nazarov

V. E.

venazarov@yandex.ru

Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет им. И. И. Мечникова» Министерства здравоохранения Российской ФедерацииNorth-Western state medical University named after I. I. Mechnikov

2024

22102024

6633138

2024

Назаров В.Е.

Nazarov V.E.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://clinendo.elpub.ru/jour/article/view/171

В статье рассматриваются вопросы диагностики Helicobacter pylori (H.pylori) с помощью быстрого уреазного теста (БУТ). Выделены особенности колонизации и персистенции H.pylori, которые влияют на результаты БУТ и определяют преимущественное использование для исследования биоптатов, а не аспирата желудочной слизи, локализацию взятия биоптатов и их оптимальное количество. Описываются особенности уреазы H.pylori и указываются факторы, влияющие на уреазную активность H.pylori. На основании описанных свойств, приводятся основные причины ошибочных результатов и методы предупреждения ложноотрицательных и ложноположительных результатов, формулируются основные правила работы с БУТ для получения оптимальных результатов.

The article discusses the problems of diagnosing Helicobacter pylori (H.pylori) using a rapid urease test (RUT). Features of H.pylori colonization and persistence are highlighted, which affect the results of RUT and determine the preferential use of biopsy specimens for the study, rather than gastric mucus aspirate, the localization of biopsy collection and their optimal number and the factors influencing the urease activity of H.pylori are indicated. Based on the described properties, the main causes of erroneous results and methods for preventing false negative and false positive results are given, the basic rules for working with RUT are formulated to obtain optimal results.

Helicobacter pyloriсвойствабыстрый уреазный тестправила

Helicobacter pyloripropertiesrapid urease testrules

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The authors declare that there are no conflicts of interest present.