clinendoКлиническая эндоскопияFilin’s Clinical endoscopy2415-7813"Global Media technology" Ltd10.31146/2415-7813-endo-63-2-35-38clinendo-121Research ArticleПУЛЬМОНОЛОГИЯPULMONOLOGYСидероз пищеводаSiderosis of the esophagusМинибаеваГ. Ф.MinibaevaG. F.noemail@neicon.ruЮцевичО. К.YutsevichO. K.noemail@neicon.ruЯгубоваЭ. А.YagubovaE. A.noemail@neicon.ruВолченкоН. Н.VolchenkoN. N.noemail@neicon.ruПироговС. С.PirogovS. S.noemail@neicon.ruКапринА. Д.KaprinA. D.noemail@neicon.ruМосковский научно-исследовательский онкологический институт имени П. А. Герцена - филиал ФГБУ «НМИЦ радиологии» Минздрава РоссииNational Medical Research Radiological Centre of the Ministry of Health of the Russian Federation2023250420246323538Copyright © Минибаева Г.Ф., Юцевич О.К., Ягубова Э.А., Волченко Н.Н., Пирогов С.С., Каприн А.Д., 20242024Минибаева Г.Ф., Юцевич О.К., Ягубова Э.А., Волченко Н.Н., Пирогов С.С., Каприн А.Д.Minibaeva G.F., Yutsevich O.K., Yagubova E.A., Volchenko N.N., Pirogov S.S., Kaprin A.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://clinendo.elpub.ru/jour/article/view/121

В настоящей публикации рассказывается о редком клиническом случае сидероза пищевода. У пациентки были обнаружены плоские неправильной формы поверхностные рубцы с участками гиперпигментации слизистой оболочки пищевода в темный цвет. Из анамнеза известно, что она долгое время страдает железодефицитной анемией и принимает препараты железа. Было выставлено заключение о поражении слизистой оболочки пищевода препаратами сульфата железа - сидероз пищевода.

This publication describes a rare clinical case of esophageal siderosis. The patient was found to have flat irregularly shaped superficial scars with areas of hyperpigmentation of the esophageal mucosa in a dark color. It is known from the anamnesis that she has long suffered from iron deficiency anemia and takes iron preparations. A conclusion was made about the defeat of the esophageal mucosa by iron sulfate preparations - esophageal siderosis. The endoscopic conclusion was confirmed by a pathomorphological study - a few cells with brown pigment in the cytoplasm were found in the subepithelial connective tissue - a picture of siderosis

сидероз пищеводалекарственный эзофагитпрепараты железажелезодефицитная анемияпервичная меланома пищеводаметастатическая меланома пищеводамеланозсидерозантракозesophageal siderosisdrug-induced esophagitisiron preparationsiron deficiency anemiaprimary esophageal melanomametastatic esophageal melanomamelanosissiderosisanthracosisReferencesAgarwal S A. et al. Esophageal Melanosis: An Unknown Entity. Cureus. 2022;9(14):e29064.Agarwal S A. et al. Esophageal Melanosis: An Unknown Entity. Cureus. 2022;9(14):e29064.Chen Z., Scudiere J. R., Montgomery E. Medication-induced upper gastrointestinal tract injury. Journal of Clinical Pathology. 2009;2 (62):113-119.Chen Z., Scudiere J. R., Montgomery E. Medication-induced upper gastrointestinal tract injury. Journal of Clinical Pathology. 2009;2 (62):113-119.Chonmaitree P.Complete Recovery from Iron-Induced Esophageal Ulcer While Continuing Pill Ingestion. Siriraj Medical Journal. 2016;6 (68):377-380.Chonmaitree P.Complete Recovery from Iron-Induced Esophageal Ulcer While Continuing Pill Ingestion. Siriraj Medical Journal. 2016;6 (68):377-380.Dubail A. et al. Esophageal Melanocytosis: report of two cases and review of a rare and misunderstood entity. Acta Gastro-Enterologica Belgica. 2022;2 (85):390-392.Dubail A. et al. Esophageal Melanocytosis: report of two cases and review of a rare and misunderstood entity. Acta Gastro-Enterologica Belgica. 2022;2 (85):390-392.Karapiperis D. et al. Primary malignant melanoma of the esophagus. Clinical Case Reports. 2022;4 (10):e05660.Karapiperis D. et al. Primary malignant melanoma of the esophagus. Clinical Case Reports. 2022;4 (10):e05660.Kaye P. et al. Iron-induced mucosal pathology of the upper gastrointestinal tract: a common finding in patients on oral iron therapy. Histopathology. 2008;3 (53):311-317.Kaye P. et al. Iron-induced mucosal pathology of the upper gastrointestinal tract: a common finding in patients on oral iron therapy. Histopathology. 2008;3 (53):311-317.Kikendall J. W. et al. Pill-induced esophageal injury. Case reports and review of the medical literature. Digestive Diseases and Sciences. 1983. № 2 (28):174-182.Kikendall J. W. et al. Pill-induced esophageal injury. Case reports and review of the medical literature. Digestive Diseases and Sciences. 1983. № 2 (28):174-182.Kuo P. et al. Education and imaging. Gastrointestinal: esophageal melanocytosis - the esophagus that seemed «off-color». Journal of Gastroenterology and Hepatology. 2011;9 (26);1463.Kuo P. et al. Education and imaging. Gastrointestinal: esophageal melanocytosis - the esophagus that seemed «off-color». Journal of Gastroenterology and Hepatology. 2011;9 (26);1463.Liu H., Yan Y., Jiang C. - M. Primary Malignant Melanoma of the Esophagus With Unusual Endoscopic Findings: A Case Report and Literature Review. Medicine. 2016;17 (95):e3479.Liu H., Yan Y., Jiang C. - M. Primary Malignant Melanoma of the Esophagus With Unusual Endoscopic Findings: A Case Report and Literature Review. Medicine. 2016;17 (95):e3479.Murata T. et al. Esophageal anthracosis: Lesion mimicking malignant melanoma. Pathology International. 2002;7 (52):488-491.Murata T. et al. Esophageal anthracosis: Lesion mimicking malignant melanoma. Pathology International. 2002;7 (52):488-491.Nandini C. L. et al. Iron-induced oesophageal injury and pigmentation. Histopathology. 2001;6 (39):643-645.Nandini C. L. et al. Iron-induced oesophageal injury and pigmentation. Histopathology. 2001;6 (39):643-645.Nasir U. M. et al. Ferrous Sulfate-Induced Esophageal Injury Leading to Esophagitis Dissecans Superficialis. Case Reports in Gastroenterology. 2020;1(14):172-177.Nasir U. M. et al. Ferrous Sulfate-Induced Esophageal Injury Leading to Esophagitis Dissecans Superficialis. Case Reports in Gastroenterology. 2020;1(14):172-177.Ohnuma H. et al. Cases of primary malignant melanoma and melanocytosis of the esophagus observed by magnifying endoscopy: Application to differential diagnosis: case series. Medicine. 2017;17 (96):e6701.Ohnuma H. et al. Cases of primary malignant melanoma and melanocytosis of the esophagus observed by magnifying endoscopy: Application to differential diagnosis: case series. Medicine. 2017;17 (96):e6701.Roquero L. et al. Esophageal Mucosal Siderosis. American Journal of Clinical Pathology. 2012;138(suppl_1):A234-A234.Roquero L. et al. Esophageal Mucosal Siderosis. American Journal of Clinical Pathology. 2012;138(suppl_1):A234-A234.Sanchez A. A. et al.Comparison of primary and metastatic malignant melanoma of the esophagus: clinicopathologic review of 10 cases. Archives of Pathology & Laboratory Medicine. 2008;10 (132):1623-1629.Sanchez A. A. et al.Comparison of primary and metastatic malignant melanoma of the esophagus: clinicopathologic review of 10 cases. Archives of Pathology & Laboratory Medicine. 2008;10 (132):1623-1629.Sharma V. et al. Esophageal ridges: an unusual complication of oral iron therapy. Annals of Gastroenterology. 2017;2 (30):250.Sharma V. et al. Esophageal ridges: an unusual complication of oral iron therapy. Annals of Gastroenterology. 2017;2 (30):250.

The authors declare that there are no conflicts of interest present.