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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая эндоскопия</journal-title><trans-title-group xml:lang="en"><trans-title>Filin’s Clinical endoscopy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2415-7813</issn><publisher><publisher-name>"Global Media technology" Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/2415-7813-endo-64-3-11-22</article-id><article-id custom-type="elpub" pub-id-type="custom">clinendo-100</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПУЛЬМОНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PULMONOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности эндоскопического адъювантного применения Митомицина-С в лечении доброкачественных стенозов дыхательных путей</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of endoscopic adjuvant use of Mitomycin-S in the treatment of benign airway stenoses</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Filin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раевская</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Raevskaya</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дуванский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Duvansky</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ Ленинградская областная клиническая Больница</institution></aff><aff xml:lang="en"><institution>Leningrad Regioal Clinical Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский университет дружбы народов</institution></aff><aff xml:lang="en"><institution>RUDN University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2024</year></pub-date><volume>64</volume><issue>3</issue><fpage>11</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козлов М.В., Филин А.А., Раевская А.Н., Дуванский В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Козлов М.В., Филин А.А., Раевская А.Н., Дуванский В.А.</copyright-holder><copyright-holder xml:lang="en">Kozlov M.V., Filin A.A., Raevskaya A.N., Duvansky V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://clinendo.elpub.ru/jour/article/view/100">https://clinendo.elpub.ru/jour/article/view/100</self-uri><abstract><p>Митомицин-С является эффективным и безопасным препаратом в лечении доброкачественных стенозов дыхательных путей, в большей степени увеличивая продолжительность безрецидивного периода, интервал между эндоскопическими манипуляциями. В связи с отсутствием четких представлений об оптимальном способе введения препарата, сроках, длительности проведения аппликации/инъекции необходимо продолжить дальнейшие исследования.</p></abstract><trans-abstract xml:lang="en"><p>Mitomycin-c is an effective and safe drug in the treatment of benign stenosis of the respiratory tract, to a greater extent increasing the duration of the relapse-free period, the interval between endoscopic manipulations. Due to the lack of clear ideas about the optimal method of administration of the drug, the timing, duration of the application / injection, it is necessary to continue further research.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>доброкачественный стеноз дыхательных путей</kwd><kwd>митомицин-С</kwd><kwd>бронхоскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>benign respiratory stenosis</kwd><kwd>Mitomycin C</kwd><kwd>bronchoscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Management of Lung Transplant Bronchial Stenosis with Mitomycin C (Kevin R. Davidson, MD2019) Bronchol Intervent Pulmonol. 2019;26:124-128) doi: 10.1097/LBR.0000000000000540.</mixed-citation><mixed-citation xml:lang="en">Management of Lung Transplant Bronchial Stenosis with Mitomycin C (Kevin R. Davidson, MD2019) Bronchol Intervent Pulmonol. 2019;26:124-128) doi: 10.1097/LBR.0000000000000540.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гасанов А. М., Хобутия М. Ш., Тарабрин Е. А., Даниелян Ш. Н., Каллагова Т. А., Ибавов И. У., Котанджян В. Г. - «Эндоскопическое лечение бронхиальных осложнений после трансплантации легких» (апрель 2021) Хирургия. Журнал им.Н.И.Пирогова; 9:12-18. doi: 10.17116/hirurgia202109112</mixed-citation><mixed-citation xml:lang="en">Гасанов А. М., Хобутия М. Ш., Тарабрин Е. А., Даниелян Ш. Н., Каллагова Т. А., Ибавов И. У., Котанджян В. Г. - «Эндоскопическое лечение бронхиальных осложнений после трансплантации легких» (апрель 2021) Хирургия. Журнал им.Н.И.Пирогова; 9:12-18. doi: 10.17116/hirurgia202109112</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">ESTS Textbook of thoracic surgery (Streitz JM, Shapsay SM. Airway injury after tracheostomy and endotracheal intubation.Surg Clin North Am.1991;71(6):1211-1230; Kastanos et al a laryngotracheal injury due to endotracheal intubation: incidence, evolution and predisposing factors. A prospective long term study. Crit Care Med. 1983;11(5):362-367</mixed-citation><mixed-citation xml:lang="en">ESTS Textbook of thoracic surgery (Streitz JM, Shapsay SM. Airway injury after tracheostomy and endotracheal intubation.Surg Clin North Am.1991;71(6):1211-1230; Kastanos et al a laryngotracheal injury due to endotracheal intubation: incidence, evolution and predisposing factors. A prospective long term study. Crit Care Med. 1983;11(5):362-367</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Паршин В. Д. Хирургия Рубцовых стенозов трахеи. - М.: Медицина. - 2003. -152 с.</mixed-citation><mixed-citation xml:lang="en">Паршин В. Д. Хирургия Рубцовых стенозов трахеи. - М.: Медицина. - 2003. -152 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">MacEwen W. Clinical Observations on the Introduction of Tracheal Tubes by the Mouth Instead of Performing Tracheotomy or Laryngotomy. Br Med J. 1880;2:122-4. doi: 10.1136/ bmj.2.1021.122</mixed-citation><mixed-citation xml:lang="en">MacEwen W. Clinical Observations on the Introduction of Tracheal Tubes by the Mouth Instead of Performing Tracheotomy or Laryngotomy. Br Med J. 1880;2:122-4. doi: 10.1136/ bmj.2.1021.122</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Colles CJI. On Stenosis of the Trachea after Tracheotomy for Croup and Diphtheria. Ann Surg. 1886;3(6):499-507.</mixed-citation><mixed-citation xml:lang="en">Colles CJI. On Stenosis of the Trachea after Tracheotomy for Croup and Diphtheria. Ann Surg. 1886;3(6):499-507.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Parshin V. D. Dissertation for the degree of Doctor of Medical Sciences on the topic: «Diagnosis, prevention and treatment of cicatricial stenosis of the trachea.» M., 2000; p.319</mixed-citation><mixed-citation xml:lang="en">Parshin V. D. Dissertation for the degree of Doctor of Medical Sciences on the topic: «Diagnosis, prevention and treatment of cicatricial stenosis of the trachea.» M., 2000; p.319</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Паршин В. Д. Хирургия рубцовых стенозов трахеи. - М., 2003. - 152с. Паршин В. Д., и соавт. Первая трансплантация реваскуляризированной трахеи больному с субтотальным рубцовым стенозом. Грудная и сердечно-сосудистая хирургия, 2007, No1, стр.64-68. Паршин В. Д., Миланов Н. О., Гудовский Л.М., Трофимов Е. И. и др. Десять лет микрохирургических технологий в реконструктивной хирургии трахеи. Грудная хирургия, 2008 г., No2, стр. 36-42.</mixed-citation><mixed-citation xml:lang="en">Паршин В. Д. Хирургия рубцовых стенозов трахеи. - М., 2003. - 152с. Паршин В. Д., и соавт. Первая трансплантация реваскуляризированной трахеи больному с субтотальным рубцовым стенозом. Грудная и сердечно-сосудистая хирургия, 2007, No1, стр.64-68. Паршин В. Д., Миланов Н. О., Гудовский Л.М., Трофимов Е. И. и др. Десять лет микрохирургических технологий в реконструктивной хирургии трахеи. Грудная хирургия, 2008 г., No2, стр. 36-42.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Stanford Lecture «Trachel and subglottic stenosis: a bronchscopist review»; 2020; https://www.youtube.com/watch?v=o-AJR3qZyoM</mixed-citation><mixed-citation xml:lang="en">Stanford Lecture «Trachel and subglottic stenosis: a bronchscopist review»; 2020; https://www.youtube.com/watch?v=o-AJR3qZyoM</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Peng Wu et al. «Nintedanib ameliorates tracheal stenosis by activating GDAC2 and suppressing IL-8 and VEGF in rabit - American Journal of translational research); Adran Ekinci et al «Profilactic role of simvastatin and mitomycin-C in tracheal stenosis after tracheal damage» 2017; Quin Enyuan et al. «Erythromycin combined with corticosteroids reduced inflammation and modified trauma-inducted tracheal stenosis in a rabbit model» 2018; Emre Turkmen et al. Prevention of tracheal stenosis with perfinedone after tracheostomy: an experimental study» 2018); Rosen G., Vered I. Y. Triamcinolone Acetoide Injection for Laryngeal stenosis. J. Laryng. 1975;89(10):1043-1046.</mixed-citation><mixed-citation xml:lang="en">Peng Wu et al. «Nintedanib ameliorates tracheal stenosis by activating GDAC2 and suppressing IL-8 and VEGF in rabit - American Journal of translational research); Adran Ekinci et al «Profilactic role of simvastatin and mitomycin-C in tracheal stenosis after tracheal damage» 2017; Quin Enyuan et al. «Erythromycin combined with corticosteroids reduced inflammation and modified trauma-inducted tracheal stenosis in a rabbit model» 2018; Emre Turkmen et al. Prevention of tracheal stenosis with perfinedone after tracheostomy: an experimental study» 2018); Rosen G., Vered I. Y. Triamcinolone Acetoide Injection for Laryngeal stenosis. J. Laryng. 1975;89(10):1043-1046.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hata T, Sano Y, et al, Mitomycin, a new antibiotic from Streptomyces. I. J. Antibiot (Tokyo) 1956;9(4):141-6.</mixed-citation><mixed-citation xml:lang="en">Hata T, Sano Y, et al, Mitomycin, a new antibiotic from Streptomyces. I. J. Antibiot (Tokyo) 1956;9(4):141-6.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Wakaki S, Marumo H, Tomioka K, Shimizu G, Kato E, Kamada H, et al. Isolation of new fractions of antitumor mitomycins. Antibiot Chemother (Northfield). 1958;8(5):228-40.</mixed-citation><mixed-citation xml:lang="en">Wakaki S, Marumo H, Tomioka K, Shimizu G, Kato E, Kamada H, et al. Isolation of new fractions of antitumor mitomycins. Antibiot Chemother (Northfield). 1958;8(5):228-40.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Occleston NL at al, single exposure to antiproliferatives: long term effects on ocular fibroblasts wound-healing behaviour. Invest Ophtalmol Vis Sci 1997; 10:1998-2007</mixed-citation><mixed-citation xml:lang="en">Occleston NL at al, single exposure to antiproliferatives: long term effects on ocular fibroblasts wound-healing behaviour. Invest Ophtalmol Vis Sci 1997; 10:1998-2007</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kunitomo N, Mori S. Studies on pterygium. Part 4. A treatment of the pterygium by mitomycin C instillation. Acta Soc Ophthalmol Jpn. 1963;67:601-7.</mixed-citation><mixed-citation xml:lang="en">Kunitomo N, Mori S. Studies on pterygium. Part 4. A treatment of the pterygium by mitomycin C instillation. Acta Soc Ophthalmol Jpn. 1963;67:601-7.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Rahbar R, Shapshay SM, Healy GB. Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. Ann Otol Rhinol Laryngol 2001;110(01):1-6. doi: 10.1177/000348940111000101</mixed-citation><mixed-citation xml:lang="en">Rahbar R, Shapshay SM, Healy GB. Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. Ann Otol Rhinol Laryngol 2001;110(01):1-6. doi: 10.1177/000348940111000101</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Ward RF, April MM. Mitomycin-C in the treatment of tra- cheal cicatrix after tracheal reconstruction. Int J Pediatr Otorhinolaryngol 1998;44:221-226.</mixed-citation><mixed-citation xml:lang="en">Ward RF, April MM. Mitomycin-C in the treatment of tra- cheal cicatrix after tracheal reconstruction. Int J Pediatr Otorhinolaryngol 1998;44:221-226.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Овчинников А. А., Середин Р. В., Середин В. П. Первый опыт применения митомицина-С в профилактике рецидива рубцового стеноза трахеи // Международный конгресс по эндохирургии. - 2003 14-16 апр. - М. - С. 272-274.</mixed-citation><mixed-citation xml:lang="en">Овчинников А. А., Середин Р. В., Середин В. П. Первый опыт применения митомицина-С в профилактике рецидива рубцового стеноза трахеи // Международный конгресс по эндохирургии. - 2003 14-16 апр. - М. - С. 272-274.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rahbar R, Shapshay SM, Healy GB. Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. Ann Otol Rhinol Laryngol 2001;</mixed-citation><mixed-citation xml:lang="en">Rahbar R, Shapshay SM, Healy GB. Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. Ann Otol Rhinol Laryngol 2001;</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hartnick CJ, Hartley BE, Lacy PD, Liu J, Bean JA, Willging JP, et al. Topical mitomycin application after laryngotracheal reconstruction: a randomized, double-blind, placebo-controlled trial. Arch Otolaryngol Head Neck Surg. 2001;127(10):1260-4. doi: 10.1001/ archotol.127.10.1260.</mixed-citation><mixed-citation xml:lang="en">Hartnick CJ, Hartley BE, Lacy PD, Liu J, Bean JA, Willging JP, et al. Topical mitomycin application after laryngotracheal reconstruction: a randomized, double-blind, placebo-controlled trial. Arch Otolaryngol Head Neck Surg. 2001;127(10):1260-4. doi: 10.1001/ archotol.127.10.1260.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Perepelitsyn I, Shapshay SM. Endoscopic treatment of laryngeal and tracheal stenosis-has mitomycin C improved the outcome? Otolaryngol Head Neck Surg 2004;</mixed-citation><mixed-citation xml:lang="en">Perepelitsyn I, Shapshay SM. Endoscopic treatment of laryngeal and tracheal stenosis-has mitomycin C improved the outcome? Otolaryngol Head Neck Surg 2004;</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Hueman EM, Simpson CB. Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg. 2005;133(6):831-5. doi: 10.1016/j.otohns.2005.07.031</mixed-citation><mixed-citation xml:lang="en">Hueman EM, Simpson CB. Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg. 2005;133(6):831-5. doi: 10.1016/j.otohns.2005.07.031</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Roh JL, Kim DH, Rha KS, et al. Benefits and risks of mitomycin use in the traumatized tracheal mucosa. Otolaryngol Head Neck Surg. 2007;136: 459-463. (25)</mixed-citation><mixed-citation xml:lang="en">Roh JL, Kim DH, Rha KS, et al. Benefits and risks of mitomycin use in the traumatized tracheal mucosa. Otolaryngol Head Neck Surg. 2007;136: 459-463. (25)</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Nouraei SA et al, Early endoscopic treatment of acute inflamattory airway lesions improves the outcome of postintubational tracheal stenosis. Laryngoscope 2006</mixed-citation><mixed-citation xml:lang="en">Nouraei SA et al, Early endoscopic treatment of acute inflamattory airway lesions improves the outcome of postintubational tracheal stenosis. Laryngoscope 2006</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Schweinfurth JM. Endoscopictreatment of severetracheal stenosis. Ann Otol.Rhinol Laryngol 2006; 115 (01): 1417/000348940611500105</mixed-citation><mixed-citation xml:lang="en">Schweinfurth JM. Endoscopictreatment of severetracheal stenosis. Ann Otol.Rhinol Laryngol 2006; 115 (01): 1417/000348940611500105</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Simpson CB, James JC. The efficacy of mitomycin-C in the treatment of laryngotracheal stenosis. Laryngoscope 2006;</mixed-citation><mixed-citation xml:lang="en">Simpson CB, James JC. The efficacy of mitomycin-C in the treatment of laryngotracheal stenosis. Laryngoscope 2006;</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ubell ML, Ettema SL, Toohill RJ, et al. Mitomycin-c application in airway stenosis surgery: analysis of safety and costs. Otolaryngol Head Neck Surg. 2006;134: 403-406.</mixed-citation><mixed-citation xml:lang="en">Ubell ML, Ettema SL, Toohill RJ, et al. Mitomycin-c application in airway stenosis surgery: analysis of safety and costs. Otolaryngol Head Neck Surg. 2006;134: 403-406.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Risk Factors for Adult Laryngotracheal Stenosis: A Review of 74 Cases.Yekaterina Koshkareva, MD; John P. Gaughan, PhD; Ahmed M. S. Soliman, MD. Аnnals of Otology, Rhinology &amp; Laryngology. 2007;116(3):206-210.</mixed-citation><mixed-citation xml:lang="en">Risk Factors for Adult Laryngotracheal Stenosis: A Review of 74 Cases.Yekaterina Koshkareva, MD; John P. Gaughan, PhD; Ahmed M. S. Soliman, MD. Аnnals of Otology, Rhinology &amp; Laryngology. 2007;116(3):206-210.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Roediger FC, Orloff LA, Courey MS. Adult subglottic stenosis: management with laser incisions and mitomycin-C. Laryngoscope 2008;118(09):1542-1546. doi: 10.1097/MLG.0b013e318179247a.</mixed-citation><mixed-citation xml:lang="en">Roediger FC, Orloff LA, Courey MS. Adult subglottic stenosis: management with laser incisions and mitomycin-C. Laryngoscope 2008;118(09):1542-1546. doi: 10.1097/MLG.0b013e318179247a.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Smith ME, Elstad M. Mitomycin C and the endoscopic treatment of laryngotracheal stenosis: are two applications better than one? Laryngoscope. 2009;119(2):272-83. doi: 10.1002/ lary.20056.</mixed-citation><mixed-citation xml:lang="en">Smith ME, Elstad M. Mitomycin C and the endoscopic treatment of laryngotracheal stenosis: are two applications better than one? Laryngoscope. 2009;119(2):272-83. doi: 10.1002/ lary.20056.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Madan K, Agarwal R, Aggarwal AN, Gupta D. Utility of rigid bronchoscopic dilatation and mitomycin C application in the management of postintubation tracheal stenosis: case series and systematic review of literature. J Bronchology Interv Pulmonol. 2012;19(04):304-310. doi: 10.1097/LBR.0b013e3182721290.</mixed-citation><mixed-citation xml:lang="en">Madan K, Agarwal R, Aggarwal AN, Gupta D. Utility of rigid bronchoscopic dilatation and mitomycin C application in the management of postintubation tracheal stenosis: case series and systematic review of literature. J Bronchology Interv Pulmonol. 2012;19(04):304-310. doi: 10.1097/LBR.0b013e3182721290.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Gouveris H, Karaiskaki N, Koutsimpelas D, Chongolwatana C, Mann W. Treatment for adult idiopathic and Wegener-associated subglottic stenosis. Eur Arch Otorhinolaryngol. 2013;270(03): 989-993. doi: 10.1007/s00405-012-2240-z.</mixed-citation><mixed-citation xml:lang="en">Gouveris H, Karaiskaki N, Koutsimpelas D, Chongolwatana C, Mann W. Treatment for adult idiopathic and Wegener-associated subglottic stenosis. Eur Arch Otorhinolaryngol. 2013;270(03): 989-993. doi: 10.1007/s00405-012-2240-z.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Parker NP, Bandyopadhyay D, Misono S, Goding GS Jr. Endoscopic cold incision, balloon dilation, mitomycin C application, and steroid injection for adult laryngotracheal stenosis. Laryngoscope. 2013;123(1):220-5. doi: 10.1002/lary.23638.</mixed-citation><mixed-citation xml:lang="en">Parker NP, Bandyopadhyay D, Misono S, Goding GS Jr. Endoscopic cold incision, balloon dilation, mitomycin C application, and steroid injection for adult laryngotracheal stenosis. Laryngoscope. 2013;123(1):220-5. doi: 10.1002/lary.23638.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Viveiros F, Gomes J, Oliveira A, Neves S, Almeida J, Moura e Sá J. Aplicação tópica de mitomicina-C como adjuvante no tratamento broncoscópico da estenose traqueal pós-entubação. Rev Port Pneumol 2013;19(06):276-280. doi: 10.1016/j.rppneu.2013.06.006.</mixed-citation><mixed-citation xml:lang="en">Viveiros F, Gomes J, Oliveira A, Neves S, Almeida J, Moura e Sá J. Aplicação tópica de mitomicina-C como adjuvante no tratamento broncoscópico da estenose traqueal pós-entubação. Rev Port Pneumol 2013;19(06):276-280. doi: 10.1016/j.rppneu.2013.06.006.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Vorasubin N, Vira D, Jamal N, Chhetri DK. Airway management and endoscopic treatment of subglottic and tracheal stenosis: the laryngeal mask airway technique. Ann Otol Rhinol Laryngol. 2014; 123(04):293-298. doi: 10.1177/0003489414525340.</mixed-citation><mixed-citation xml:lang="en">Vorasubin N, Vira D, Jamal N, Chhetri DK. Airway management and endoscopic treatment of subglottic and tracheal stenosis: the laryngeal mask airway technique. Ann Otol Rhinol Laryngol. 2014; 123(04):293-298. doi: 10.1177/0003489414525340.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Early Endoscopic Dilation and Mitomycin Application in the Treatment of Acquired Tracheal Stenosis, Ruben Ortiz 2014, doi: 10.1055/s-0033-1357754; Eur J Pediatr Surg 2014; 24(01): 039-045.</mixed-citation><mixed-citation xml:lang="en">Early Endoscopic Dilation and Mitomycin Application in the Treatment of Acquired Tracheal Stenosis, Ruben Ortiz 2014, doi: 10.1055/s-0033-1357754; Eur J Pediatr Surg 2014; 24(01): 039-045.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Reichert LK, Zhao AS, Galati LT, Shapshay SM. The efficacy of mitomycin c in the treatment of laringotracheal stenosis: results and experiences with a difficult disease entity. ORL J Otorhinolar- yngol Relat Spec 2015;77(06):351-358. doi: 10.1159/000439174.</mixed-citation><mixed-citation xml:lang="en">Reichert LK, Zhao AS, Galati LT, Shapshay SM. The efficacy of mitomycin c in the treatment of laringotracheal stenosis: results and experiences with a difficult disease entity. ORL J Otorhinolar- yngol Relat Spec 2015;77(06):351-358. doi: 10.1159/000439174.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Cataneo DC, Ximenes AMG, Cataneo AJM. Mitomycin C in the endoscopic treatment of tracheal stenosis: a prospective cohort study. J Bras Pneumol. 2018;44(06):486-490. doi: 10.1590/S1806-37562017000000423.</mixed-citation><mixed-citation xml:lang="en">Cataneo DC, Ximenes AMG, Cataneo AJM. Mitomycin C in the endoscopic treatment of tracheal stenosis: a prospective cohort study. J Bras Pneumol. 2018;44(06):486-490. doi: 10.1590/S1806-37562017000000423.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Yung KC, Chang J, Courey MS A. A randomized controlled trial of adjuvant mitomycin-c in endoscopic surgery for laryngotracheal stenosis. Laryngoscope. 2019 Apr 25. doi: 10.1002/lary.28025.</mixed-citation><mixed-citation xml:lang="en">Yung KC, Chang J, Courey MS A. A randomized controlled trial of adjuvant mitomycin-c in endoscopic surgery for laryngotracheal stenosis. Laryngoscope. 2019 Apr 25. doi: 10.1002/lary.28025.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Thereza Queiroga «Mitomycin C in the Endoscopic Treatment of laryngotracheal Stenosis: Systematic Review and proportional Meta-Analysis» - Int Arch Otorhinolaryngol 2020; 24: e112-e124. doi: 10.1055/s-0039-1700582.</mixed-citation><mixed-citation xml:lang="en">Thereza Queiroga «Mitomycin C in the Endoscopic Treatment of laryngotracheal Stenosis: Systematic Review and proportional Meta-Analysis» - Int Arch Otorhinolaryngol 2020; 24: e112-e124. doi: 10.1055/s-0039-1700582.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Fiberoptic Bronchoscopic Submucosal Injection of Mitomycin C for Recurrent Bening Tracheal Stenosis: A Case Series; Arch Otolaryngol Head Neck Surg. 2002;128(4):401-406. doi:10.1001/archotol.128.4.401.</mixed-citation><mixed-citation xml:lang="en">Fiberoptic Bronchoscopic Submucosal Injection of Mitomycin C for Recurrent Bening Tracheal Stenosis: A Case Series; Arch Otolaryngol Head Neck Surg. 2002;128(4):401-406. doi:10.1001/archotol.128.4.401.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Submucosal Injection of Mitomycin C in a Case of Vanishing Bronchus After Lung TransplantMehmet Furkan Sahin, Sinan Turkkan, Muhammet Ali Beyoglu, Alkin Yazicioglu, Erdal Yekeler-2020. doi: 10.6002/ect.2020.0203.</mixed-citation><mixed-citation xml:lang="en">Submucosal Injection of Mitomycin C in a Case of Vanishing Bronchus After Lung TransplantMehmet Furkan Sahin, Sinan Turkkan, Muhammet Ali Beyoglu, Alkin Yazicioglu, Erdal Yekeler-2020. doi: 10.6002/ect.2020.0203.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Wright et al The Annals of Thoracic Surgery 108.5 (2019) 1471-477.</mixed-citation><mixed-citation xml:lang="en">Wright et al The Annals of Thoracic Surgery 108.5 (2019) 1471-477.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Gerachenko TI et al «Complications of tracheal intubation and tracheostomy after longterm assisted lung ventilation in children». Voprosy prakticheskoi pediatrii. 2015; 10(5):68-72.</mixed-citation><mixed-citation xml:lang="en">Gerachenko TI et al «Complications of tracheal intubation and tracheostomy after longterm assisted lung ventilation in children». Voprosy prakticheskoi pediatrii. 2015; 10(5):68-72.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Farzanegan R et al «An Overview of Tracheal stenosis Research Trends and hot Topics. Arch Iran Med.2017;20(9):598-607.</mixed-citation><mixed-citation xml:lang="en">Farzanegan R et al «An Overview of Tracheal stenosis Research Trends and hot Topics. Arch Iran Med.2017;20(9):598-607.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">E. L. Atkova et al., «Mitomycin C after endoscopic endonasal dacryoctorynostomy» doi: 10.17116/oftalma201733516-22.</mixed-citation><mixed-citation xml:lang="en">E. L. Atkova et al., «Mitomycin C after endoscopic endonasal dacryoctorynostomy» doi: 10.17116/oftalma201733516-22.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">in Reference to A Randomized Controlled Trial of Adjuvant Mitomycin-C in Endoscopic Surgery for Laryngotracheal Stenosis The Laryngoscope 2020 The American Laryngological, Rhinological and Otological Society, Inc. F. Dikkers et al. doi: 10.1002/lary.28834.</mixed-citation><mixed-citation xml:lang="en">in Reference to A Randomized Controlled Trial of Adjuvant Mitomycin-C in Endoscopic Surgery for Laryngotracheal Stenosis The Laryngoscope 2020 The American Laryngological, Rhinological and Otological Society, Inc. F. Dikkers et al. doi: 10.1002/lary.28834.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Reinke JM, Sorg H. Wound repair and regeneration. Eur Surg Res. 2012;49: 35-43.</mixed-citation><mixed-citation xml:lang="en">Reinke JM, Sorg H. Wound repair and regeneration. Eur Surg Res. 2012;49: 35-43.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Landén NX, Li D, Ståhle M. Transition from inflammation to proliferation: a critical step during wound healing. Cell Mol Life Sci. 2016;73:3861-3885.</mixed-citation><mixed-citation xml:lang="en">Landén NX, Li D, Ståhle M. Transition from inflammation to proliferation: a critical step during wound healing. Cell Mol Life Sci. 2016;73:3861-3885.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Hirshoren N, Eliashar R. Wound-healing modulation in upper airway stenosis - myths and facts. Head Neck. 2009;31:111-126.</mixed-citation><mixed-citation xml:lang="en">Hirshoren N, Eliashar R. Wound-healing modulation in upper airway stenosis - myths and facts. Head Neck. 2009;31:111-126.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Schultz GS, Wysocki A. Interactions between extracellular matrix and growth factors in wound healing. Wound Repair Regen. 2009;17:153-162.</mixed-citation><mixed-citation xml:lang="en">Schultz GS, Wysocki A. Interactions between extracellular matrix and growth factors in wound healing. Wound Repair Regen. 2009;17:153-162.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Li NY, Chen F, Dikkers FG, Thibeault SL. Dose-dependent effect of mitomy- cin C on human vocal fold fibroblasts. Head Neck. 2014;36:401-410.</mixed-citation><mixed-citation xml:lang="en">Li NY, Chen F, Dikkers FG, Thibeault SL. Dose-dependent effect of mitomy- cin C on human vocal fold fibroblasts. Head Neck. 2014;36:401-410.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Katherine Young et al in Reply to Mitomycin-C Is Ineffective in Laryngotracheal Surgery If Used Incorrectly The Laryngoscope 2020 The American Laryngological, Rhinological and Otological Society, Inc. doi: 10.1002/lary.28838.</mixed-citation><mixed-citation xml:lang="en">Katherine Young et al in Reply to Mitomycin-C Is Ineffective in Laryngotracheal Surgery If Used Incorrectly The Laryngoscope 2020 The American Laryngological, Rhinological and Otological Society, Inc. doi: 10.1002/lary.28838.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Yung KC, Chang J, Courey MS. A randomized controlled trial of adjuvant mitomycin-c in endoscopic surgery for laryngotracheal stenosis. Laryngoscope. 2020;130:706-711. doi: 10.1002/lary.28025.</mixed-citation><mixed-citation xml:lang="en">Yung KC, Chang J, Courey MS. A randomized controlled trial of adjuvant mitomycin-c in endoscopic surgery for laryngotracheal stenosis. Laryngoscope. 2020;130:706-711. doi: 10.1002/lary.28025.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Khaw PT, Doyle JW, Sherwood MB, Grierson I, Schultz G, McGorray S. Pro- longed localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. Arch Ophthalmol. 1993;111:263-267.</mixed-citation><mixed-citation xml:lang="en">Khaw PT, Doyle JW, Sherwood MB, Grierson I, Schultz G, McGorray S. Pro- longed localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. Arch Ophthalmol. 1993;111:263-267.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Netto MV, Mohan RR, Sinha S, Sharma A, Gupta PC, Wilson SE. Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. J Refract Surg. 2006;22:562-574.</mixed-citation><mixed-citation xml:lang="en">Netto MV, Mohan RR, Sinha S, Sharma A, Gupta PC, Wilson SE. Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. J Refract Surg. 2006;22:562-574.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Gouveris H, Karaiskaki N, Koutsimpelas D, Chongolwatana C, Mann W. Treatment for adult idiopathic and Wegener-associated subglottic steno- sis. Eur Arch Otorhinolaryngol 2013;270:989-993.</mixed-citation><mixed-citation xml:lang="en">Gouveris H, Karaiskaki N, Koutsimpelas D, Chongolwatana C, Mann W. Treatment for adult idiopathic and Wegener-associated subglottic steno- sis. Eur Arch Otorhinolaryngol 2013;270:989-993.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Smith ME, Elstad M. Mitomycin C and the endoscopic treatment of laryngotracheal stenosis: are two applications better than one? Laryngoscope. 2009;119:272-283.</mixed-citation><mixed-citation xml:lang="en">Smith ME, Elstad M. Mitomycin C and the endoscopic treatment of laryngotracheal stenosis: are two applications better than one? Laryngoscope. 2009;119:272-283.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Silva Merea V, Bryson PC. Office-based retrograde transtracheal applica- tion of mitomycin C. Am J Otolaryngol. 2018;39:704-706.</mixed-citation><mixed-citation xml:lang="en">Silva Merea V, Bryson PC. Office-based retrograde transtracheal applica- tion of mitomycin C. Am J Otolaryngol. 2018;39:704-706.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Eliashar R, Eliachar I, Esclamado R, Gramlich T, Strome M. Can topical mitomycin prevent laryngotra- cheal stenosis? Laryngoscope. 1999;109:1594-1600.</mixed-citation><mixed-citation xml:lang="en">Eliashar R, Eliachar I, Esclamado R, Gramlich T, Strome M. Can topical mitomycin prevent laryngotra- cheal stenosis? Laryngoscope. 1999;109:1594-1600.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Cincik H, Gungor A, Cakmak A, et al. The effects of mi- tomycin C and 5-fluorouracil/triamcinolone on fibrosis/ scar tissue formation secondary to subglottic trauma (experimental study). Am J Otolaryngol. 2005;26:45-50.</mixed-citation><mixed-citation xml:lang="en">Cincik H, Gungor A, Cakmak A, et al. The effects of mi- tomycin C and 5-fluorouracil/triamcinolone on fibrosis/ scar tissue formation secondary to subglottic trauma (experimental study). Am J Otolaryngol. 2005;26:45-50.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Hardillo J, Vanclooster C, Delaere PR. An investigation of airway wound healing using a novel in vivo model. Laryngoscope. 2001;111:1174-1182.</mixed-citation><mixed-citation xml:lang="en">Hardillo J, Vanclooster C, Delaere PR. An investigation of airway wound healing using a novel in vivo model. Laryngoscope. 2001;111:1174-1182.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Roh JL. Prevention of posterior glottic stenosis by mitomycin C. Ann Otol Rhinol Laryngol. 2005;114:558-562.</mixed-citation><mixed-citation xml:lang="en">Roh JL. Prevention of posterior glottic stenosis by mitomycin C. Ann Otol Rhinol Laryngol. 2005;114:558-562.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Spector JE, Werkhaven JA, Spector NC. et al. Preserva- tion of function and histologic appearance in the injured glottis with topical mitomycin-C. Laryngoscope. 1999; 109(7 Part 1):1125-1129.</mixed-citation><mixed-citation xml:lang="en">Spector JE, Werkhaven JA, Spector NC. et al. Preserva- tion of function and histologic appearance in the injured glottis with topical mitomycin-C. Laryngoscope. 1999; 109(7 Part 1):1125-1129.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Garrett CG, Soto J, Riddick J, Billante CR, Reinisch L. Effect of mitomycin-C on vocal fold healing in a canine model. Ann Otol Rhinol Laryngol. 2001;110:25-30.</mixed-citation><mixed-citation xml:lang="en">Garrett CG, Soto J, Riddick J, Billante CR, Reinisch L. Effect of mitomycin-C on vocal fold healing in a canine model. Ann Otol Rhinol Laryngol. 2001;110:25-30.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Roh JL, Kim DH, Rha KS, Sung MW, Kim KH, Park CI. Benefits and risks of mitomycin use in the traumatized tracheal mucosa. Otolaryngol Head Neck Surg. 2007; 136:459-463.</mixed-citation><mixed-citation xml:lang="en">Roh JL, Kim DH, Rha KS, Sung MW, Kim KH, Park CI. Benefits and risks of mitomycin use in the traumatized tracheal mucosa. Otolaryngol Head Neck Surg. 2007; 136:459-463.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Roh JL, Lee YW, Park CI. Can mitomycin C really pre- vent airway stenosis? Laryngoscope. 2006;116:440-445.</mixed-citation><mixed-citation xml:lang="en">Roh JL, Lee YW, Park CI. Can mitomycin C really pre- vent airway stenosis? Laryngoscope. 2006;116:440-445.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Coppit G, Perkins J, Munaretto J, Nielsen R, McKinney L, Ulnick K. The effects of mitomycin-C and stenting on airway wound healing after laryngotracheal reconstruc- tion in a pig model. Int J Pediatr Otorhinolaryngol. 2000;53:125-135.</mixed-citation><mixed-citation xml:lang="en">Coppit G, Perkins J, Munaretto J, Nielsen R, McKinney L, Ulnick K. The effects of mitomycin-C and stenting on airway wound healing after laryngotracheal reconstruc- tion in a pig model. Int J Pediatr Otorhinolaryngol. 2000;53:125-135.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Correa AJ, Reinisch L, Sanders DL, et al. Inhibition of subglottic stenosis with mitomycin-C in the canine model. Ann Otol Rhinol Laryngol. 1999;108(11 Part 1):1053-1060.</mixed-citation><mixed-citation xml:lang="en">Correa AJ, Reinisch L, Sanders DL, et al. Inhibition of subglottic stenosis with mitomycin-C in the canine model. Ann Otol Rhinol Laryngol. 1999;108(11 Part 1):1053-1060.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Eliashar R, Gross M, Maly B, Sichel JY. Mitomycin does not prevent laryngotracheal repeat stenosis after endo- scopic dilation surgery: an animal study. Laryngoscope. 2004;114:743-746.</mixed-citation><mixed-citation xml:lang="en">Eliashar R, Gross M, Maly B, Sichel JY. Mitomycin does not prevent laryngotracheal repeat stenosis after endo- scopic dilation surgery: an animal study. Laryngoscope. 2004;114:743-746.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Shvidler J, Bothwell NE, Cable B. Refining indications for the use of mitomycin C using a randomized con- trolled trial with an animal model. Otolaryngol Head Neck Surg. 2007;136:653-657.</mixed-citation><mixed-citation xml:lang="en">Shvidler J, Bothwell NE, Cable B. Refining indications for the use of mitomycin C using a randomized con- trolled trial with an animal model. Otolaryngol Head Neck Surg. 2007;136:653-657.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Spector JE, Werkhaven JA, Spector NC, Huang S, Sand- ers D, Reinisch L. Prevention of anterior glottic resteno- sis in a canine model with topical mitomycin-C. Ann Otol Rhinol Laryngol. 2001;110:1007-1010.</mixed-citation><mixed-citation xml:lang="en">Spector JE, Werkhaven JA, Spector NC, Huang S, Sand- ers D, Reinisch L. Prevention of anterior glottic resteno- sis in a canine model with topical mitomycin-C. Ann Otol Rhinol Laryngol. 2001;110:1007-1010.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Roh JL, Yoon YH. Prevention of anterior glottic stenosis after bilateral vocal fold stripping with mitomycin C. Arch Otolaryngol Head Neck Surg. 2005; 131:690-695.</mixed-citation><mixed-citation xml:lang="en">Roh JL, Yoon YH. Prevention of anterior glottic stenosis after bilateral vocal fold stripping with mitomycin C. Arch Otolaryngol Head Neck Surg. 2005; 131:690-695.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">David W. Eisele MD «Wound healing modulation in upper airway stenosis-myths and facts»2008 Wiley Periodicals; doi: 10.1002/hed.20925.</mixed-citation><mixed-citation xml:lang="en">David W. Eisele MD «Wound healing modulation in upper airway stenosis-myths and facts»2008 Wiley Periodicals; doi: 10.1002/hed.20925.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Кирасирова Е. А. 2004 г. Москва - «Реабилитация больных с повреждением гортани разной этиологии»- Докторская диссертация.</mixed-citation><mixed-citation xml:lang="en">Кирасирова Е. А. 2004 г. Москва - «Реабилитация больных с повреждением гортани разной этиологии»- Докторская диссертация.</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Google patents - https://patents.google.com/patent/RU2775937C1/ru</mixed-citation><mixed-citation xml:lang="en">Google patents - https://patents.google.com/patent/RU2775937C1/ru</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Национальные клинические рекомендации по оториноларингологии от 2021 года - «Хронические рубцовые стенозы гортани».</mixed-citation><mixed-citation xml:lang="en">Национальные клинические рекомендации по оториноларингологии от 2021 года - «Хронические рубцовые стенозы гортани».</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Wound healing cascade an update review - Hani Sinno and Satya Prakash - plastic surgery international. doi: 10.1155/2013/146764.</mixed-citation><mixed-citation xml:lang="en">Wound healing cascade an update review - Hani Sinno and Satya Prakash - plastic surgery international. doi: 10.1155/2013/146764.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
